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IBT.V - Ibex Technologies inc

Aujourd’hui je vais introduire une micro-cap de Montréal dans le domaine biomédicale. Cette compagnie à des revenues irrégulier d’un trimestre à l’autre et on pourrais dire illiquide sur le marché présentement. Donc ne conviens pas à tout les investisseurs. Étant donné que je ne suis pas biochimiste, je vais essayer de vous expliquez le mieux possible ce qu’il font.

IIBEX Technologies Inc. est une société cotée en bourse cotée à la Bourse de croissance TSX (IBT.V).
La Société exerce ses activités principalement par le biais d’IBEX Pharmaceuticals Inc (située à Montréal, Québec, Canada)

L’activité principale d’IBEX Pharmaceutical est la fabrication et la vente d’enzymes de haute pureté pour le diagnostic et la recherche in vitro. La Société fabrique et vend également des kits d’arthrose (ELISA) pour la recherche préclinique.
IBEX Pharmaceutical fournit des services importants aux grandes sociétés in vitro:
Remplissage et lyophilisation des composants de diagnostic jetables. Fermentation personnalisée.

Jusqu’au 31 juillet 2019, IBEX produisait ses enzymes sur ses sites de Montréal, au Québec et de North Liberty, Iowa, ainsi que dans une usine de fabrication tierce surveillée par le personnel IBEX. Au 31 juillet, 2019, l’usine de l’Iowa a été fermée et la production des produits fabriqués sur ce site a été transférée sur le site de Montréal.

L’un des produits phare de Ibex est l’héparinase qui est qui est largement utilisés dans la recherche, la production d’héparine de bas poids moléculaire(low molecular weight heparin (LMWH)) , et en conjonction avec des dispositifs cliniques de surveillance de l’hémostase.
Jusqu’ici je me dois d’expliqué l’héparine, l’héparinase ainsi que l’hémostase.

Héparine: L’héparine est un médicament anticoagulant
Héparine de bas poids moléculaire: anticoagulants qu’on administre par injections sous-cutanées
Héparinase: Enzyme qui catalyse le clivage d’une liaison chimique des héparines.
Hémostase: Ensemble des phénomènes physiologiques permettant d’arrêter un saignement en cas de rupture d’un vaisseau sanguin.

Pourquoi Ibex?
Malgré le manque de croissance Ibex est une compagnie avec 3M en cash et a une capitalisation boursière modeste cependant la crise de Covid-19 pourrais être un catalyseur pour cette compagnie. Il semblerait que certains patients de covid-19 développent des signes d’épaississement du sang et de coagulation et que l’héparine LMWH est la solution. J’en conclus que cette compagnie pourrais avoir une augmentation de ses ventes dans les prochains trimestres.
quelques liens à propos,
Alarmed as COVID patients’ blood thickened, New York doctors try new treatments

Why Is COVID-19 Coronavirus Causing Strokes In Young And Middle-Aged People?

Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy

SARS-CoV2 by inhibition of host cell proteases?

Au 31 janvier 2020, la Société disposait d’un fonds de roulement net de 2,832,532 $ par rapport au fonds de roulement net de 2,838,173 $ au 31 juillet 2019.
La trésorerie à augmenté de 423,922 $ soit 3,003,781 $ par rapport au 31 juillet 2019.

Symbole boursier : IBT.V

Site web: https://www.ibex.ca/

Prix de l’action au 26 avril 2020: $0.19

Actions émises et en circulation: 24,773,244

Capitalisation boursière: $4.7M

Dernier rapport trimestriel: IBEX Technologies earns $35,460 in Q2 2020

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Un autre article dans la presse qui vient juste de paraître. Une autre mauvaise surprise de la COVID-19: des caillots de sang

Tres belle découverte, merci de la partager sur le forum! Ca donne le gout den apprendre d’avantage sur cette compagnie et de l’Heparinase.

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Compagnie intéressante effectivement! Je la suis depuis des années et j’ai déjà parlé au management. Malheureusement, c’est très difficile de faire des prévisions futures pour Ibex (même le CEO a de la difficulté) et c’est ce qui m’a toujours retenu d’acheter le titre malgré la valorisation plus que raisonnable.

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Un autre étude intéressante

Un nouveau haut de 52 semaines pour IBT.V
voici un peu plus d’information sur les actions détenus par les initiés

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Un essai clinique pour vérifier si l’héparine peut traiter la COVID-19

Mine de rien, l’action de IBT.V s’envole tranquillement, anonymus à acheté plus de 300k d’actions depuis le 19 mai dont certain bloc de 100K. ce qui est beaucoup pour un titre illiquide. Les résultats financier sont prévus pour le mois de juin. On pourra en savoir plus à partir de ce moment.

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@midard as tu plus d’infos sur l’utilisation de l’heparine dans le traitement de la covid 19 . Je crois quil y a une étude en cours presentement pour tester son efficacité?

voir le lien que j’ai mis il y à 8 jours

Un autre chose que je peux rajouter, Ibex à comme client Haemonetics Corporation est un fournisseur mondial de fournitures et de services pour les produits sanguins HAE:NYSE. cette compagnie fabriques des machines de diagnostiques de l’hémostase selon ce document cette analyseur est utilisé dans les cas de Covid-19

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IBEX Reports Results for the Third Quarter and the Nine Months Ended April 30, 2020
MONTRÉAL, June 24, 2020 (GLOBE NEWSWIRE) – IBEX Technologies Inc. (“IBEX” or the “Company”) (TSX Venture: IBT) today reported its financial results for the nine months ended April 30, 2020.

“We were pleased to see near record sales in the current quarter as compared to an exceptionally poor quarter year ago. Some of this gain, however, may have been the result of customers advancing orders to secure their supply chain, which may have a negative impact on subsequent quarters”, said Mr. Baehr IBEX President & CEO. “With year-to-date sales up 20% over year ago our financial picture has improved considerably during this fiscal year. Thus far we have not been negatively impacted by the COVID-19 environment”.

Note: All figures are in Canadian dollars unless otherwise stated. The Company’s audited consolidated financial statements for the year ended July 31, 2019 and the accompanying notes and the related management’s discussion and analysis can be found on the Company’s website at www.ibex.ca or under the Company’s profile on SEDAR at www.sedar.com.

FINANCIAL RESULTS FOR THE THIRD QUARTER OF FISCAL 2020

Revenues for the quarter ended April 30, 2020 totaled $1,679,409 and were up $1,010,900 compared to $668,509 in the same period of the prior year. The increase in revenues traces mainly to changes in quarterly purchasing patterns on the part of several of our major customers. It is possible that some customers may have advanced their order due to the COVID-19 situation.

Operating Expenses at $1,052,972 were down $134,237, tracing mainly to the closure of our facility in Iowa.

As a result, the Company recorded EBITDA of positive $769,335 vs. EBITDA of negative $452,119 in same period year ago.

It should be noted that “EBITDA” (Earnings Before Interest, Tax, Depreciation & Amortization) is not a performance measure defined by IFRS, but IBEX, as well as investors and analysts, consider that this performance measure facilitates the evaluation of our ongoing operations and our ability to generate cash flows to fund our cash requirements, including our capital expenditures program. Note that other public companies may use alternative definitions.

EBITDA for the three months ended
April 30, 2020 April 30, 2019
Net earnings (loss) $ 626,437 $ (518,700 )
Depreciation of property, plant, equipment and intangible assets $ 56,862 $ 69,453
Depreciation of right-of-use assets $ 42,561 -
Impairment of property, plant and equipment $ 37,000 -
Interest - Net $ 6,475 $ (2,872 )
Earnings (loss) before interest, taxes, depreciation and amortization $ 769,335 $ (452,119 )

The Company recorded net earnings for the period of $626,437 compared to a net loss of $518,700 for the same period year ago. The positive change of $1,145,137 is related mainly to the increase in revenues and a decrease in expenses as discussed above.

FINANCIAL RESULTS FOR THE NINE MONTHS ENDED APRIL 30, 2020

Revenues for the nine months ended April 30, 2020 of $3,763,010 were up $622,396 as compared to $3,140,614 in the same period of the prior year. The increase in revenues traces to the factor mentioned above.

Operating Expenses at $3,101,113 were down $724,144, tracing mainly to the closure of our facility in Iowa and to a positive inventory adjustment of $140,795 (the difference between goods produced for inventory and the goods sold).

As a result of the above, the Company recorded positive EBITDA of $1,020,922 vs. a negative $478,038 EBITDA in the same period year ago.

The Company recorded net earnings of $661,897 compared to a net loss of $684,643 for the same period year ago. This positive variation can be mainly traced to the decrease in expenses result from to the closure of our Iowa facility and the increase in revenues.

Cash and cash equivalents increased by $263,271 to $2,843,130 during the nine months ended April 30, 2020 as compared to the year ended July 31, 2019. Net working capital increased by $765,151 to $3,603,324 during the nine months ended April 30, 2020 as compared to the year ended July 31, 2019.

Financial Summary for the nine months ended
April 30, 2020 April 30, 2019
Revenues $ 3,763,010 $ 3,140,614
Earnings (loss) before interest, tax, depreciation & amortization (EBITDA) $ 1,020,922 $ (478,038 )
Depreciation of property, plant, equipment and intangible assets $ 174,895 $ 210,522
Depreciation of right-of-use assets $ 126,986 -
Impairment of property, plant and equipment $ 37,000 -
Net earnings (loss) $ 661,897 $ (684,643 )
Earnings (loss) per share $ 0.03 $ (0.03 )

EBITDA for the nine months ended
April 30, 2020 April 30, 2019
Net earnings (loss) $ 661,897 $ (684,643 )
Depreciation of property, plant, equipment and intangible assets $ 174,895 $ 210,522
Depreciation of right-of-use assets $ 126,986 -
Impairment of property, plant and equipment $ 37,000 -
Interest - Net $ 20,144 $ (3,917 )
Earnings (loss) before interest, taxes, depreciation and amortization $ 1,020,922 $ (478,038 )

Balance Sheet Summary as at
April 30, 2020 April 30, 2019
Cash and cash equivalents $ 2,843,130 $ 2,980,584
Net working capital $ 3,603,324 $ 3,068,584
Outstanding shares at report date (common shares) 24,773,244 24,773,244

SALE OF BRP’S ASSETS

The Company closed operations at its North Liberty, Iowa production facility on July 31, 2019 and the facility was put up for sale. During the third quarter, the Company accepted an offer from a third party to purchase the land, buildings and equipment owned by the Company’s Bio-Research Products subsidiary in Iowa. The transaction closed on June 19, 2020.

Therefore, as at April 30, 2020, criteria for their classification as assets held for sale has been met. The assets have been stated at the lower of carrying value and fair value less costs to sell. The Company has taken a non-cash impairment of approximately $37,000 related to the land, buildings and equipment.

The sale will have a small positive cash impact after transaction fees and paying off the $723,527 USD mortgage.

From an operational point of view, the Company expects the sale of the site will reduce annual expenses by approximately $170,000 USD per annum.

As previously reported, the production of all major products which IBEX acquired during the purchase of BRP have been moved to Montréal and represent an important augmentation to the IBEX product portfolio.

COVID-19

As an “Essential Service” (producing reagents and components for critical care diagnostic tests), IBEX has remained operational, albeit with significant changes in the way we operate (administrative staff work mainly from home and production and lab staff are on site on an as-needed basis) and COVID-19 has not thus far impacted our ability to produce and sell.

Our financial picture has actually improved over the last quarter, as customers have increased their purchases of our products (which mainly end up in diagnostics used in hospitals), however like many companies in the medical environment we do not have a clear picture of how COVID-19 will impact future sales.

The COVID-19 situation has had an impact on some of our developmental programs which rely heavily on external suppliers, some of which have been closed down as a result of the pandemic. We expect some of these programs to resume in the fourth quarter.

LOOKING FORWARD

As always, the future financial results of the Company are difficult to predict as the Company’s customers have significant variations in their purchasing patterns, as can has been illustrated in the current year’s quarterly results.

Based on what we see at this time, we expect Fiscal 2020 revenues to be somewhat higher than last year, and with the reduction in expenses resulting from the closure of the Iowa production facility, we expect to be net earnings positive for the year.

The Company continues to work on a number of new heparinase-containing clinical device projects with its key customers, some of which may result in additional revenues in Fiscal 2021 and beyond; however, as with all developmental projects, we cannot give any assurances that any of these customer-driven projects will come to market and produce significant revenues.

ABOUT IBEX

IBEX manufactures and markets proteins for biomedical use through its wholly owned subsidiaries IBEX Pharmaceuticals Inc. (Montréal, QC). IBEX Pharmaceuticals also manufactures and markets a series of arthritis assays which are widely used in osteoarthritis research.

For more information, please visit the Company’s website at www.ibex.ca.

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Ibex à rajouté plusieurs enzymes à sa gamme de produits, il est maintenant distributeur pour la compagnie 3Helix

https://www.3helix.com/

L’héparinase (heparine lyase) d’Ibex est utilisé dans la recherche sur le Covid, https://www.biorxiv.org/content/10.1101/2020.07.14.201616v1.full.pdf

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La demande pour l’héparinase est vraiment là.
CPC Biotech steps up heparinases production as CV-19 coronavirus response

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Ibex est un titre non promotionnel et ce titre va générer des profits grâce au Covid. l’héparine est maintenant utilisé dans presque tout les patients de la Covid et est même en essai clinique à travers le monde comme potentiel traitement. A chaque fois qu’on utilise de l’héparine, des test de l’hémostase doive être effectué, la plupart des tests utilise de l’héparinase.
Selon le site d’Ibex
Heparinase 1 rapidly and specifically neutralizes both unfractionated heparin as well as low molecular weight heparin, allowing baseline hemostasis to be monitored in the presence of these anticoagulants.
As a result, Heparinase I is incorporated into disposables from a number of leading diagnostic companies, and is in development for additional diagnostic uses

Voici un exemple d’une machine thromboelastography (TEG) de la compagnie Haemonetics un client d’Ibex. L’héparinase est utilisé dans la cassette qui s’insère dans la machine.
https://www.youtube.com/watch?v=64mjmKOH3I4&t

En bonus l’heparinase (heparin lyase)pourrait servir de potentiel traitement
Abstract
We show that SARS-CoV-2 spike protein interacts with cell surface heparan sulfate and
angiotensin converting enzyme 2 (ACE2) through its Receptor Binding Domain. Docking studies
suggest a putative heparin/heparan sulfate-binding site adjacent to the domain that binds to
ACE2. In vitro, binding of ACE2 and heparin to spike protein ectodomains occurs independently
and a ternary complex can be generated using heparin as a template. Contrary to studies with
purified components, spike protein binding to heparan sulfate and ACE2 on cells occurs
codependently. Unfractionated heparin, non-anticoagulant heparin, treatment with heparin
lyases, and purified lung heparan sulfate potently block spike protein binding and infection by
spike protein-pseudotyped virus and SARS-CoV-2 virus. These findings support a model for
SARS-CoV-2 infection in which viral attachment and infection involves formation of a complex
between heparan sulfate and ACE2. Manipulation of heparan sulfate or inhibition of viral
adhesion by exogenous heparin may represent new therapeutic opportunities.

peu de potentiel une fois la covid passé

Un autre bon trimestre avec des ventes d’héparinase relié à l’utilisation d’héparine pour la Covid-19.
revenues annuel de 5,2M Ibex est sous-évalué présentement avec une capitalisation de 6,6 M.
IBEX Technologies earns $965,689 in fiscal 2020

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IBEX Technologies earns $150,066 in Q1 2021
$0.16 l’action en cash

Pour ceux qui sont intéressés, une entrevue avec Paul Andreola.

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Bon résultats pour Ibex:

Le titre se transige à un ratio EV/EBITDA d’environ 2,3x. Le marché donne clairement très peu de crédit à l’entreprise. Si ces résultats sont soutenables à plus long terme, le titre semble être toute une aubaine.

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