IPA.V - ImmunoPrecise Antibodies Ltd


#162

Même après l’octroi d’options, Robert Burke ajoute à sa position sur le marché :


#163

ImmunoPrecise Appoints Lisa Helbling as Chief Financial Officer


#164

C’est modeste pour l’instant mais je pense que plusieurs investisseurs seront contents de voir la CEO acheter sur le marché :


#165

Présentation au Noble Healthcare Conference en Floride cette semaine

Le lien pour la conférence https://www.nobleconference.com/NobleCon15/about.htm


#166

Lien direct … question de vous sauvez du temps :slight_smile:

http://noble.mediasite.com/mediasite/Play/861820a85571404ba887a06b868f82201d?catalog=88b4f8c61c9e48d6a6aab5f4bfb5550f21


#167

Présentations pour investisseurs


#168

IPA sera a BioCeo, NY la semaine prochaine BIOCEO


#169

ImmunoPrecise Antibodies Ltd. Increases Antibody Discovery Capabilities with Addition of Integrated Laboratory Equipment for High-throughput Antibody Screening

VICTORIA, Feb. 5, 2019 /CNW/ - IMMUNOPRECISE ANTIBODIES LTD. (the “Company” or “IPA”) (TSX VENTURE: IPA) (OTC PINK: IPATF) has announced the purchase of its second state-of-the-art Intellicyt® iQue Screener PLUS for high-throughput cell-based screening.

The demand for accelerated development of next-generation antibodies that recognize evermore challenging targets and have improved activities has prompted IPA to purchase further instrumentation to evaluate more antibody characteristics in a multiplexed, high-throughput way. Traditional antibody screening tools report on binding one target at a time, which makes the discovery process time consuming and can require large amounts of target protein. The Intellicyt iQue allows IPA scientists to significantly reduce lead discovery time while conserving valuable samples and reducing reagent cost.

“The decision to acquire a second Intellicyt iQue [now for North America] will further support IPA’s strategic vision of continued growth and expansion in providing end-to-end therapeutic antibody discovery services to a rapidly expanding list of pharma and biotech clients.” said Jennifer Bath, CEO and President of ImmunoPrecise Antibodies.

The iQue Screener PLUS can analyze antibodies developed from all of IPA’s antibody discovery platforms, hybridoma, B cell select, and phage display, on cells or beads in suspension. The early stage screening of antibodies on cell surface targets provides more predictable data and enables the selection of lead candidate drugs earlier and faster. In addition, the iQue provides early data on the activities of lead drugs to improve the probability for downstream successes.

About ImmunoPrecise Antibodies Ltd.

ImmunoPrecise is a full-service, therapeutic and diagnostic antibody discovery company focused on the next generation of antibody discovery, to deliver the most relevant antibodies, in a shorter period of time, with the highest probability of succeeding through clinical validation.

ImmunoPrecise Antibodies Ltd operates from three state-of-the-art laboratory facilities. ImmunoPrecise Antibodies (Canada) is located in Victoria, British Columbia, while U-Protein Express B.V., and ModiQuest Research B.V. are located in Utrecht and Oss, Netherlands, respectively. The Company operates globally to offer antibody services from target analysis to pre-clinical studies.

The services offered to clients include antibody discovery for a broad spectrum of antigens, including challenging targets. Among these services, the Company offers antibody development directly from B-cells (B-Cell Select), through phage display, and by hybridoma production. The Company also provides a broad range of supporting services including immunologically-based assays, recombinant protein manufacturing, humanization, optimization, stable cell line development, and advanced solutions to challenges faced by clients in antibody-related research and development. The antibodies produced by ImmunoPrecise target a wide variety of therapeutic, diagnostic and research applications.


#170

Second US Office for ImmunoPrecise Antibodies, Ltd. in Cambridge, Massachusetts

Canada NewsWire

VICTORIA, Feb. 14, 2019

VICTORIA, Feb. 14, 2019 /CNW/ - IMMUNOPRECISE ANTIBODIES LTD. (the “Company” or “IPA”) (TSX VENTURE: IPA) (OTC PINK: IPATF) has announced that they have opened a new subsidiary office in Cambridge, Massachusetts.

image: https://mma.prnewswire.com/media/822089/ImmunoPrecise_Antibodies_Ltd__Second_US_Office_for_ImmunoPrecise.jpg

ImmunoPrecise Antibodies Ltd. (CNW Group/ImmunoPrecise Antibodies Ltd.)

ImmunoPrecise Antibodies Ltd is a Canadian contract research organization providing a range of services, including antibody discovery, manufacturing, optimization, engineering and pre-clinical studies.

“With production sites in Canada and the Netherlands, and the executive headquarters in the North Dakota, establishing a base in the Boston / Cambridge area, a powerhouse for biotech and pharma, is a strategic next step for IPA. We already have a strong base of both European and US clients, and this move will help us enhance and grow our Boston area business and relationships”, said Jennifer Bath, CEO of IPA.

The new office is located at One Broadway, 14th floor, Cambridge, MA 02142 and will initially be staffed for sales and business development initiatives.

“There is a tremendous demand for pioneering antibody discovery and development services in the greater Boston area, the largest US biotech hub, and we are excited to provide day-to-day access to our clients and prospective clients as we continue to offer an unparalleled continuum of antibody discovery and downstream technologies,” stated Dr. Jennifer Bath, CEO and President of IPA.

Read more at https://stockhouse.com/news/press-releases/2019/02/14/second-us-office-for-immunoprecise-antibodies-ltd-in-cambridge-massachusetts#XlFI48xbH6EXtwTT.99


#171

Je pense qu’avec la session d’aujourd’hui IPA vient de concéder une partie de son mystère dans sa structure. Voyons voir avec les prochaines séances si le Drapeau se confirme.


#173

ImmunoPrecise Antibodies Collaborates with FIND to Help Advance New TB Diagnostic Test

VICTORIA, Feb. 19, 2019 /CNW/ - IMMUNOPRECISE ANTIBODIES LTD. (the “Company” or “IPA”) (TSX VENTURE: IPA) (OTC PINK: IPATF) announces the publication of the results of a research collaboration project with the Foundation for Innovative New Diagnostics (FIND) where IPA developed rabbit monoclonal antibodies (mAbs) for assessment in FIND’s sensitive new immunoassay diagnostic test for tuberculosis (TB). IPA developed rabbit monoclonal antibodies, using its B cell Select platform, that recognize lipoarabinomannan (LAM), a lipopolysaccharide target and biomarker for TB that can be excreted in the urine of individuals with the disease. Two of these antibodies, when combined with others to form capture-detection pairs and a sensitive chemical detection reagent, were highly specific for LAM and sensitive enough to detect LAM in urine samples.

ImmunoPrecise Antibodies Ltd. (CNW Group/ImmunoPrecise Antibodies Ltd.)

FIND believes that early diagnosis is crucial for achieving the goal of decreasing the estimated 1.7 million deaths caused by tuberculosis each year. Developing an affordable point-of-care diagnostic that is sensitive enough to accurately detect the disease in easily-obtainable samples is a challenging, but critical part of achieving that goal.

IPA’s propriety B cell Select platform enables antibody discovery directly from the B cells derived from tissues of many species of animal, including rabbits, while maintaining the antibodies’ native heavy and light chain pairings. “Organizations that develop immunoassays as diagnostic tests depend on the discovery of sensitive and specific mAbs. These reagents form the foundation for dependable diagnostics that could ultimately increase the early diagnosis and thus decrease the effects of many diseases worldwide,” said Jennifer Bath, President and CEO of ImmunoPrecise Antibodies.

“We are pleased with the outcome of this successful collaboration,” said Claudia Denkinger, Head of Tuberculosis program at FIND. “Just 3 months after immunization we were able to use the high-affinity rabbit monoclonal antibody developed by ImmunoPrecise in a sensitive assay to detect the tuberculosis antigen. The antibody was highly specific with excellent affinities.”

The scientific publication titled: A Novel Sensitive Immunoassay Targeting the 5-Methylthio-d-Xylofuranose–Lipoarabinomannan Epitope Meets the WHO’s Performance Target for Tuberculosis Diagnosis, was published in the Journal of Clinical Microbiology 2018 Dec; 56(12)

About ImmunoPrecise Antibodies Ltd.

ImmunoPrecise is a full-service, therapeutic and diagnostic antibody discovery company focused on the next generation of antibody discovery, to deliver the most relevant antibodies, in a shorter period of time, with the highest probability of succeeding through clinical validation.

ImmunoPrecise Antibodies Ltd operates from three state-of-the-art laboratory facilities. ImmunoPrecise Antibodies (Canada) is located in Victoria, British Columbia, while U-Protein Express B.V., and ModiQuest Research B.V. are located in Utrecht and Oss, Netherlands, respectively. The Company operates globally to offer antibody services from target analysis to pre-clinical studies.

The services offered to clients include antibody discovery for a broad spectrum of antigens, including challenging targets. Among these services, the Company offers antibody development directly from B-cells (B-Cell Select), through phage display, and by hybridoma production. The Company also provides a broad range of supporting services including immunologically-based assays, recombinant protein manufacturing, humanization, optimization, stable cell line development, and advanced solutions to challenges faced by clients in antibody-related research and development. The antibodies produced by ImmunoPrecise target a wide variety of therapeutic, diagnostic and research applications.

About FIND:

FIND (Foundation for Innovative New Diagnostics) is an international non-profit organization that enables the development and delivery of much-needed diagnostic tests for poverty-related diseases, including tuberculosis, malaria, HIV/AIDS, sleeping sickness, hepatitis C, leishmaniasis, Chagas disease, Buruli ulcer, febrile illnesses and infectious diseases with outbreak potential, such as Ebola.

FIND acts as a bridge between experts in technology development, policy and clinical care, reducing barriers to innovation and effective implementation of diagnostic solutions in low- and middle-income countries.


#174

Le contrat a une valeur approximative de $5M USD pour l’instant. Ce secteur est en changement rapide et ce genre de partenariat va devenir une norme.

ImmunoPrecise Antibodies Receives Subcontract to Produce Rabbit Monoclonal Antibodies

VICTORIA, Feb. 21, 2019 /CNW/ - IMMUNOPRECISE ANTIBODIES LTD. (the “Company” or “IPA”) (TSX VENTURE: IPA) (OTC PINK: IPATF) has received a five-year Indefinite Delivery/Indefinite Quantity (ID/IQ) subcontract from Leidos Biomedical Research, Inc., which currently operates the Frederick National Laboratory for Cancer Research for the National Cancer Institute (NCI). Under the subcontract, IPA will discover and produce rabbit monoclonal antibodies using its proprietary B-Cell Select platform.

ImmunoPrecise Antibodies Ltd. (CNW Group/ImmunoPrecise Antibodies Ltd.)

The rabbit monoclonal antibodies discovered and produced under this subcontract will be used in the key applications of immunohistochemistry and immuno-Multiple Reaction Monitoring (immuno-MRM). The antibodies will be generated for NCI’s Antibody Characterization Program. Immuno-MRM is a leading-edge targeted mass spectrometry technique that relies on antibodies to enrich peptides from complex biological samples that are then quantified by mass spectrometry. Rabbit monoclonal antibodies are highly sought after for this purpose because they exhibit high specificity and bind their target with high affinity. Immuno-MRM is being used to discover novel biomarkers and develop a new generation of clinical diagnostic tests that could lead to improved cancer detection, diagnosis, and treatment.

IPA’s B-Cell Select platform enables rabbit monoclonal antibody discovery directly from B-cells through recombinant DNA cloning and expression of antibody gene sequences. This process allows for large panels of antibodies to be screened for functionality via multiple methods to pick the most relevant leads for the final application and can be applied to discover antibodies from several species for diagnostics and therapeutics.

“We are very pleased to work with Leidos Biomedical to support the world-class cancer research funded by NCI and NIH globally. We look forward to applying IPA’s experience and expertise in developing rabbit monoclonal antibodies to the challenging projects being advanced through Leidos” said Deanna Dryhurst, CSO of IPA.

About Frederick National Laboratory for Cancer Research

The Frederick National Laboratory for Cancer Research is dedicated to improving human health through discovery and innovation in the biomedical sciences, focusing on cancer, AIDS, and rapid response to emerging infectious diseases. Frederick National Laboratory is operated by Leidos Biomedical Research, Inc. for the National Cancer Institute.

About ImmunoPrecise Antibodies Ltd.

ImmunoPrecise is a full-service, therapeutic antibody discovery company focused on the next generation of antibody discovery, to deliver the most therapeutically-relevant antibodies, in a shorter period of time, with the highest probability of succeeding to clinical trials.

ImmunoPrecise operates from state-of-the-art laboratory facilities located at the Vancouver Island Technology Park in Victoria, British Columbia, in collaboration with its wholly-owned subsidiary operations at U-Protein Express B.V., in the Life Science Incubator, Utrecht, and ModiQuest Research, Oss, both in the Netherlands. The Company operates globally to offer antibody services from target analysis to pre-clinical studies.

The services offered to clients include antibody discovery against a broad spectrum of antigens, including challenging targets. Amongst these services, the Company offers hybridoma production, B-cell services, and a variety of phage display platforms. The Company also provides a broad range of supporting services including immunologically-based assays, recombinant protein manufacturing, humanization, optimization, stable cell line development, and advanced solutions to challenges faced by clients in antibody-related research and development. The antibodies produced by ImmunoPrecise target a wide variety of therapeutic, diagnostic and research applications.


#175

ImmunoPrecise Antibodies Announces DTC Eligibility

VICTORIA, BC, Feb. 28, 2019 /CNW/ - IMMUNOPRECISE ANTIBODIES LTD. (the “Company” or “IPA”) (TSX VENTURE: IPA) (OTC PINK: IPATF) is pleased to announce that its common shares are now eligible for electronic clearing and settlement through the Depository Trust Company (" DTC ") in the United States.

DTC is a subsidiary of the Depository Trust & Clearing Corporation, a U.S. company that manages the electronic clearing and settlement of publicly traded companies. Securities that are eligible to be electronically cleared and settled through DTC are considered to be “DTC eligible”. DTC eligibility is expected to simplify the process of trading and enhance liquidity of the Company’s common shares in the United States.

“The ability to have ImmunoPrecise shares electronically transferred between brokerages in the United States is significantly more convenient and reduces the costs incurred in trading shares,” stated Lisa Hebling, CFO of ImmunoPrecise. “With our shares now traded electronically, existing investors benefit from greater liquidity and execution speed s , while we’ve also opened the door to new investors that may have been previously restricted from our stock.”


#176

IPA est en processus de produire à l’interne ses propres cibles. Fort de ses capacités de production la compagnie va développer un nouveau pipeline de revenu avec royautés attachés par projet. Cette acquisition met en perspective le valorisation de seulement quelques cibles.

Merck to Acquire Immune Design

Acquisition Bolsters Capabilities in Vaccine Development for Infectious Diseases and Cancer

KENILWORTH, N.J. & SEATTLE & SOUTH SAN FRANCISCO, Calif.–(BUSINESS WIRE)-- Merck (MRK), known as MSD outside the United States and Canada, and Immune Design (IMDZ), today announced that the companies have entered into a definitive agreement under which Merck, through a subsidiary, will acquire Immune Design for $5.85 per share in cash for an approximate value of $300 million.

This press release features multimedia. View the full release here:https://www.businesswire.com/news/home/20190221005198/en/

“Scientists at Immune Design have established a unique portfolio of approaches to cancer immunization and adjuvant systems designed to enhance the ability of a vaccine to protect against infection, which could meaningfully improve vaccine development," said Dr. Roger M. Perlmutter, president, Merck Research Laboratories. “This acquisition builds upon Merck’s industry-leading programs that harness the power of the immune system to prevent and treat disease.”

Immune Design is a late-stage immunotherapy company employing next-generation in vivo approaches to enable the body’s immune system to fight disease. The company’s proprietary technologies, GLAAS® and ZVex®, are engineered to activate the immune system’s natural ability to generate and/or expand antigen-specific cytotoxic immune cells to fight cancer and other chronic diseases.

“Merck has a rich history of discovery and innovation and a strong track record of developing meaningful therapeutics and vaccines,” said Dr. Carlos Paya, president and chief executive officer, Immune Design. “We believe this agreement creates shareholder value by positioning our technologies and capabilities for long-term success with a leading, research-driven biopharmaceutical company.”

Under the terms of the acquisition agreement announced today, Merck, through a subsidiary, will initiate a tender offer to acquire all outstanding shares of Immune Design. The closing of the tender offer will be subject to certain conditions, including the tender of shares representing at least a majority of the total number of Immune Design’s outstanding shares, the expiration of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act and other customary conditions. Upon the successful completion of the tender offer, Merck will acquire all shares not acquired in the tender through a second-step merger. The transaction is expected to close early in the second quarter of 2019.

Credit Suisse acted as financial advisor to Merck in this transaction and Gibson, Dunn & Crutcher LLP as its legal advisor. Lazard acted as financial advisor to Immune Design and Cooley LLP as its legal advisor.

Important Information about the Tender Offer

The tender offer described in this press release (the “Offer”) has not yet commenced. This press release is for informational purposes only and is neither an offer to purchase nor a solicitation of an offer to sell any shares of the common stock of Immune Design or any other securities. At the time the planned tender offer is commenced, a tender offer statement on Schedule TO, including an offer to purchase, a letter of transmittal and related documents, will be filed by Merck Sharp & Dohme Corp. (“Merck”) and Cascade Merger Sub Inc., a wholly-owned subsidiary of Merck (“Buyer”), with the Securities and Exchange Commission (the “SEC”), and a solicitation/recommendation statement on Schedule 14D-9 will be filed by Immune Design with the SEC. The offer to purchase shares of Immune Design common stock will only be made pursuant to the offer to purchase, the letter of transmittal and related documents filed as a part of the Schedule TO.

INVESTORS AND SECURITY HOLDERS ARE URGED TO READ BOTH THE TENDER OFFER STATEMENT AND THE SOLICITATION/RECOMMENDATION STATEMENT REGARDING THE OFFER, AS THEY MAY BE AMENDED FROM TIME TO TIME, WHEN THEY BECOME AVAILABLE BECAUSE THEY WILL CONTAIN IMPORTANT INFORMATION.

Investors and security holders may obtain a free copy of these statements (when available) and other documents filed with the SEC at the website maintained by the SEC at www.sec.gov or by directing such requests to the Information Agent for the Offer, which will be named in the tender offer statement. Additional copies of the tender offer materials may be obtained at no charge by contacting Merck at 2000 Galloping Hill Road, Kenilworth, N.J., 07033 or by phoning (908) 423-1000. In addition, Merck and Immune Design file annual, quarterly and current reports and other information with the SEC. You may read and copy any reports or other information filed by Merck or Immune Design at the SEC public reference room at 100 F Street, N.E.,Washington, D.C., 20549. For further information on the SEC public reference room, please call 1-800-SEC-0330. Merck’s and Immune Design’s filings with the SEC are also available to the public from commercial document-retrieval services and at the SEC’s website at www.sec.gov.

About Merck

For more than a century, Merck, a leading global biopharmaceutical company known as MSD outside of the United States and Canada, has been inventing for life, bringing forward medicines and vaccines for many of the world’s most challenging diseases. Through our prescription medicines, vaccines, biologic therapies and animal health products, we work with customers and operate in more than 140 countries to deliver innovative health solutions. We also demonstrate our commitment to increasing access to health care through far-reaching policies, programs and partnerships. Today, Merck continues to be at the forefront of research to advance the prevention and treatment of diseases that threaten people and communities around the world - including cancer, cardio-metabolic diseases, emerging animal diseases, Alzheimer’s disease and infectious diseases including HIV and Ebola. For more information, visit www.merck.com and connect with us on Twitter, Facebook, Instagram,YouTube and LinkedIn.

About Immune Design

Immune Design is a late-stage immunotherapy company employing next-generation in vivo approaches to enable the body’s immune system to fight disease. The company’s technologies are engineered to activate the immune system’s natural ability to generate and/or expand antigen-specific cytotoxic immune cells to fight cancer and other chronic diseases. G100, the company’s lead product candidate, is a potent intratumoral TLR4 agonist that has shown clinical benefit in multiple tumor types. Immune Design’s technologies, the fundamental components of which were licensed from the California Institute of Technology and the Infectious Disease Research Institute (IDRI), also have potential application in infectious disease and allergy indications, which are being developed through ongoing pharmaceutical collaborations. Immune Design has offices in Seattle and South San Francisco. For more information, please visit www.immunedesign.com.